Study Sets

Tutorial in neoplastic hematology 01

Compiled by: Ahmad Alkhasawneh

Lymphocytosis in middle age patient

61-year-old male presented with leukocytosis to primary care physician. CBC result, representative cells from differential and representative bone marrow are provided. Work up (including immunohistochemistry on tissue, flow cytometry, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".

Blasts versus atypical monocytes

62-year-old woman admitted with worsening dyspnea on exertion and found to have leukocytosis. CBC result, representative cells from differential and representative bone marrow are provided. Work up (including immunohistochemistry on tissue, flow cytometry, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".

Possible blasts in blood

77-year-old man with history of chronic pancytopenia and macrocytosis. No prior therapy. 7% Atypical cells were noted in the differential count (see images).CBC result, representative cells from differential and representative bone marrow are provided. #Note: Subclassification is required. Work up (including immunohistochemistry on tissue, flow cytometry, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".

Atypical cells on blood smear

66-year-old man with history of asthma, intermittent fever and borderline leukocytosis. CBC result, representative cells from differential and representative bone marrow are provided. Note: Subclassification is required. Work up (including immunohistochemistry on tissue, flow cytometry, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".

Neutrophilia with left shift.

51-year-old women admitted with worsening lower back pain and found to have severe leukocytosis. Work up (including immunohistochemistry on tissue, flow cytometry, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".

Back pain from a compression fracture

58-year-old man with acute on chronic back pain and found to have compression fracture L2. Lab findings are shown, and bone marrow biopsy was performed. Representative cells from marrow aspirate smears and representative bone marrow are provided. Work up (including immunohistochemistry on tissue, flow cytometry, SPEP, free light chains, karyotype, FISH, and molecular), morphology guide for blood smear and flow cytometry guide are available under "specials to order".